Computer Simulations of Biological Molecules on the NGS

There is a new case study now available from the NGS website on the use of NGS resources to NGS resources to try and understand how biological molecules perform their functions.

Sarah Harris from the University of Leeds has most recently used the NGS to study the fragmentation of long filamentous structures formed from aggregated proteins which are known as amyloid fibrils. These are associated with a number of degenerative diseases in humans including Alzheimer’s, Parkinson’s and type II diabetes.

Sarah explained “The NGS has provided us with additional computational resources which have enabled us to perform more accurate calculations than would otherwise have been possible. It has also acted as a nucleation point for researchers using high performance computing in the UK. This exchange of ideas has lead to our research group considering new ways in which we can perform our calculations more efficiently and on a far larger scale in the future”.  

To read more about Sarah’s research, see the "Computer Simulations of Biological Molecules at the Atomic Level” case study.